PLATELETS FROM PATIENTS WITH MYELOPROLIFERATIVE NEOPLASMS HAVE INCREASED NUMBERS OF MITOCHONDRIA THAT ARE HYPERSENSITIVE TO DEPOLARIZATION BY THROMBIN

Platelets from patients with myeloproliferative neoplasms have increased numbers of mitochondria that are hypersensitive to depolarization by thrombin

Abstract Thrombosis is one of the cardinal manifestations of myeloproliferative neoplasms (MPN).The mechanisms leading to a prothrombotic state in MPN Hoods are complex and remain poorly understood.Platelet mitochondria play a role in platelet activation, but their number and function have not been extensively explored in MPN to date.We observed an

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Transgressive subversions? Female religious leaders in Hinduism

As the eminent (female) anthropologist Mary Douglas (1966) pointed out, the "social body" constrains and contrives the way the physical body is perceived and obligated into performance.The physical experience ofthe body is in turn often modified by a clutch of regulatory and panoptic religio-social categories through which it is known and made to r

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